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Insulin Sensitivity: GLP-1 levels that are high demonstrate strong insulin sensitivity whereas low GLP-1 levels can be an indicator of insulin resistance which leads to type 2 diabetes

PubMed Central, Ravanbakhsh, Naseem, and Anil Kesavan
Semaglutide as a Cardiovascular Disease Modifier: Semaglutide belongs to the class of medications known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which have been found to offer cardioprotective effects beyond glycemic control

The change from baseline in HbA1c at week 40 corresponds to the primary endpoint in SURPASS2 and SUSTAIN FORTE

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