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these cytokines are produced primarily by adipocytes, tissue-resident macrophages, and infiltrating immune cells (e.g., Th17 cells and other T lymphocytes) within the adipose tissue, which can exacerbate keratinocyte activation and immune dysregulation in psoriatic skin (48)

Updated Usage and Awareness Recent CivicScience tracking through mid-December found that 16% of U.S

(30) In a second study, Magruder et al

they are also expressed in various tissues throughout the body, including immune cells and vascular endothelium, with some preliminary evidence suggesting potential presence in synovial tissue
