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Clinical trials show users lose 1015% of body weight over 68 weeks when combining the medication with modest dietary changes, not extreme calorie cutting

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Because of its long half-life of about one week, semaglutide remains in the body for several weeks after the last dose, so effects (both therapeutic and side effects) can persist even after stopping

Increased clinical monitoring of thyroid parameters should also be considered when treating patients with both semaglutide and oral levothyroxine

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