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Cost-effectiveness of GLP-1 receptor agonists versus insulin for the treatment of type 2 diabetes: a real-world study and systematic review

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Some experimental data suggest that acute LPS exposure can suppress FMO expression, indicating that the relationship between LPS and TMAO may depend on the duration of the diet and the level of inflammation 53,55,56 While no significant difference in TMAO levels was observed between the groups in our study, the decrease in LPS, recovery of barrier proteins, and improvement in lipid profile support the conclusion that semaglutide treatment reduces endotoxemia-induced cardiometabolic load 51,57