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If meaningful progress hasn't appeared by week 8, your PlexusDx clinician may recommend a dose increase, a switch to GLP-Squared dual-compound therapy, or genetic testing to identify underlying peptide pathway predispositions

Semaglutide is known to reduce body weight, largely via appetite suppression, in patients with obesity 5,6 and in adult mouse models 30,31

Safety Considerations and Provider-Guided Eligibility Combining HGH and semaglutide is not appropriate for everyone

PlexusDx tirzepatide injection ($249/mo) allows dose customization, while oral tirzepatide ($279/mo) offers convenience at the trade-off of variable absorption

Tirzepatide is a glucose-dependent insulinotropic polypeptide/GLP- 1 dual receptor agonist (GIP/GLP- 1 RA) and in the Phase 3 SURMOUNT- 1 trial, tirzepatide 5 mg, 10 mg and 15 mg produced mean weight reduction from baseline to week 72 of 15,0%, 18.5% and 20.9%, respectively, versus 2.4% for placebo

5 Canadian Address Validation for Plan Member (Province and Postal Code) Checks that Province is selected/entered as a valid Canadian province/territory and that Postal Code matches Canadian format (A1A 1A1) and is consistent with the province when possible