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There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop, said senior author Ziyad Al-Aly, MD, a WashU Medicine clinical epidemiologist and chief of the Research and Development Service at the VA Saint Louis Health Care System

Further translational research and prospective clinical trials are required to clarify causality, determine effect size, and identify high-risk groups most likely to benefit

At 13 to 24 months following prescription, participants experienced a 3.8 per cent drop from baseline weight, with those without diabetes seeing even greater reductions of 5.1 per cent

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Referral to an endocrinologist may be appropriate for: Persistent symptoms with normal TSH Goitre or thyroid nodules Uncertain diagnosis Pregnancy or planning pregnancy Failed control with standard treatment Significant TSH abnormalities Patient education is essential

Comparing Formulations: Clear vs