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A.Loizides-MangoldU.GaaN.LazarevicV.De VitoC.et al (2021)
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Retatrutide: A triple incretin receptor agonist for obesity management

However, to date, there is only one randomized clinical trial of GLP-1 RAs (the ELIXA study) evaluating major cardiovascular events as their primary outcomes, and in this study, a neutral cardiovascular effect of lixisenatide was observed in high-risk diabetic subjects

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Epithelial NAD(+) depletion drives mitochondrial dysfunction and contributes to intestinal inflammation
