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Recombinant CHO-K1 cells stably overexpress human glucagon-like peptide-1 receptor (GLP1R) on the surface and contain high levels of G protein Gs to couple with the receptor in downstream signaling pathways.

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Compared to placebo, patients receiving liraglutide had significantly greater weight loss after 6-month therapy [MD6.0 kg (95% CI,8.66 to3.33)