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NICE guidance (NG28) recommends GLP-1 receptor agonists as treatment options for adults with type 2 diabetes when metformin and other oral therapies have not achieved adequate glycaemic control, or when there are specific clinical considerations such as significant obesity or high cardiovascular risk

PubMed Objective: Although the pathogenesis of non-alcoholic fatty liver disease (NAFLD) has been extensively studied, the role of its underlying pathogenesis remains unclear, and there is currently no approved therapeutic strategy for NAFLD

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Health conditions such as diabetes and hypoglycemia can significantly affect your blood sugar levels

Furthermore, the purpose of this review is to discuss the putative mechanisms by which specific bacterial metabolites, such as short chain fatty acids, trigger GLP-1 secretion through GPR41/43-dependent mechanisms