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Description
In vitro, mouse pancreatic -cells (NIT-1 cells) were exposed to palmitic acid (PA), PA+exendin-4 (Ex-4), PA+GW, PA+GSK0660 (GSK, a PPAR antagonist), or PA+Ex-4+GSK

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Kezia Parkins asks the experts

Its pathogenesis is unknown
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These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite.