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Isotretinoin is a potent derivative of vitamin A, a retinoid, that's reserved almost exclusively for treating severe, recalcitrant nodular acne that hasn't responded to other treatments

The segment is currently dominated by Eli Lilly's weight loss molecule Mounjaro (tirzepatide), which holds about 79% share, while Novo's semaglutide accounts for around 21% as of February-end

*Correspondence: Arjola Bano, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Oral tirzepatide is in clinical trials, and if successful, could eliminate the injection barrier entirely for this class

Remember that 5 to 8 percent body weight in three months is significant and sustainable