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Read the instructions carefully before use

Monitor the color of your urine

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GLP-1 receptor activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, reduces appetite signaling, and slows gastric emptying in research models GIP receptor activation potentiates insulin secretion in a glucose-dependent manner, modulates adipose tissue metabolism, and contributes to energy balance regulation in preclinical studies The dual incretin mechanism produces additive and potentially synergistic effects on insulin secretion and metabolic regulation compared to GLP-1 receptor activation alone

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However, while the Gly10D-Ala analogue was indistinguishable from the native hormone in terms of potency (EC 50 ), the Gly10L-Ala was ~24-fold less potent (Fig