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BW higher than 22.5 kg/m 2 has been observed to increase CVD and T2D risk substantially, contributing to more than 30% of global human mortality

Further, the CVOTs in general also suggested a potential benefit of GLP-1 RAs on HF, positioning GLP-1 RAs as another advanced option alongside SGLT2 inhibitors in the otherwise sparse treatment armamentarium for especially HFpEF

In 2023, she was looking to see if she was a candidate for bariatric surgery

Age and metabolic baseline matter too, as younger patients sometimes respond faster than older populations, though older adults still achieve excellent long-term outcomes

General principles for restarting GLP-1 medications include: Adequate oral intake : You should be tolerating a normal diet (or your usual post-operative diet plan) without significant nausea or vomiting Resolution of post-operative ileus : Normal bowel function should have returned, particularly after abdominal or pelvic surgery Stable clinical condition : Any post-operative complications should be resolved, and you should be recovering as expected Medical team approval : Always confirm with your surgical team or GP before restarting If you've been off a GLP-1 medication for several weeks, your doctor may recommend re-titrating the dose (starting at a lower dose and gradually increasing) to minimise gastrointestinal side effects when restarting
