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Notably, GLP-1RAs benefit pain management through their neuroprotective and metabolic regulatory properties, such as inhibiting inflammation responses and oxidative stress, promoting -endorphin release and modulating several other crucial biological pathways

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Theres no evidence that they have any sort of substantially lingering effect once you stop taking them, said Patrick ONeil, Ph.D., director of the MUSC Weight Management Center and a professor in the Department of Psychiatry and Behavioral Sciences