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Using a standard health economics method to classify health improvements and cost savings into dollars, the researchers found that people without college diplomas saved $219,000 to $220,000, while that amount fell for college-educated individuals to $163,000

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Importantly, despite modest heart rate increases, cardiovascular outcomes trials have not demonstrated increased cardiovascular risk

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Nat Med 2024;30:205866

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10.2337/diabetes.52.1.124 24 ChangC

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Meanwhile, LSN3318839, an orally effective positive allosteric modulator selective for GLP-1(9-36), anchors in the TM1-TM2 cleft and repositions GLP-1(9-36) to adopt a binding pose like GLP-1(7-36), thereby enhancing GLP-1R-mediated signal transduction

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