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In rare cases, GLP-1 agonists may cause serious side effects, including allergic reactions, pancreatitis, gallbladder disease, and kidney disease.[ref][ref] Obviously, talk with your doctor about the risks vs

Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials

You still enjoy eating, but it doesn't drive behavior in the same way" [17]

Barnett M et al

This information matters for several reasons

What raises concerns are some of the recent reports of serious ADRs associated with GLP-1RAs: (i) Pfizers disclosure of elevated aminotransferases in users of lotiglipron (a novel oral GLP-1RA) is indicative of hepatocellular injury [11]