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The majority of studies indicate that both short- and long-acting GLP-1RAs reduce energy intake in health (27), obesity (55-59), T1D (60), and T2D (22, 27, 61-63) with only 1 study (with liraglutide in T2D) failing to show a significant reduction in energy intake compared to placebo (28) [Fig

Semaglutide wins on everything that requires time: approval, safety data, cardiovascular outcomes

What the Research Shows Recent research on semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) has revealed concerning trends about body composition changes: A 2023 analysis of STEP trial data found that approximately 39% of weight lost on semaglutide was lean body mass 1 Research on tirzepatide showed similar patterns, with 30-40% of total weight loss coming from lean tissue 2 Comparative studies indicate GLP-1 users may lose more muscle than people losing weight through diet and exercise alone 3 For context: if you lose 50 pounds on a GLP-1 medication, 15-20 pounds might be muscle mass

Pushing past your tolerance window creates exactly the kind of GI mess that makes patients quit the protocol entirely

If its been more than 6 months After a six month gap in treatment, youll need to restart at the lowest dose

Here are four dietitian-approved strategies for incorporating ice cream into a diabetes-friendly diet