glp-1 news november 2025 Harvard Medical School Researcher Wins Breakthrough Prize for Work on glp-1 news november 2025 Patients

BIBLIOGRAPHY 1 - Tirzepatide PI 2 - PMID 34170647 - Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes, NEJM (2021) 3 - PMID 35133415 - Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial, JAMA (2022) 4 - North Carolina Pharmacy Practice Act

It also discusses the benefits of natural compounds that modulate GLP-1 and highlights the importance of finding alternatives to injectable GLP-1 receptor agonists (GLP-1RAs)

The reference lists of all publications were queried to detect studies not identified during the initial search

doi: 10.1124/pr.115.011395

injections of 100 nmol kg 1 MK-801, 100 nmol kg 1 GLP-1, 10 nmol kg 1 semaglutide, 100 nmol kg 1 GLP-1MK-801 or vehicle immediately before onset of the dark cycle at a volume of 2 ml kg 1

The presence of GLP-1 receptors in these reward pathways has prompted researchers to investigate whether GLP-1 agonists might influence behaviours beyond eating, including alcohol consumption