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Most are well tolerated when introduced gradually

After the exclusion of 9,075 patients due to prior anti-obesity medication, and 72,731 patients for bipolar, schizophrenia, depressive disorders, anxiety and suicide ideation or attempts within 1 year before, the treatment cohort numbered 162,257 patients

doi: 10.1113/jphysiol.1970.sp009155 [DOI] [PMC free article] [PubMed] [Google Scholar] 11

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At the moment, some medications can collaborate in the treatment of MASLD, some of them approved for the treatment of comorbidities such as GLP-1 agonists indicated for the treatment of T2DM or obesity, but also with benefit in the MASH treatment (9, 10)

As a result, the absence of increased cancer incidence in short-to mid-term follow-up cannot be equated with long-term oncological safety