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In addition, brain insulin resistance affects tau metabolism and promotes the hyperphosphorylation of tau proteins, tau protein aggregation, the formation of paired helical filaments, and the further formation of NFTs (You et al., 2022)

In a study comparing 25 PWS patients and 25 obese individuals, irisin levels were significantly lower in PWS patients with a del15q compared to obese controls, while patients with a mUPD did not show significant differences compared to controls ( Table 4 )

When discussing this with your healthcare provider, bring the evidence

You can also talk with your doctor about the differences between Ozempic and Wegovy

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