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A Direct Look at the Phase 2 Numbers Does Retatrutide Cause Hair Loss
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In a Phase II study reported in 2024 involving 168 patients with NASH, moderate to advanced fibrosis (F2F3), and NAS 4, a significantly greater proportion of patients in the denifanstat group achieved the primary endpoint compared with placebo, with statistically meaningful improvements in fibrosis as well
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For researchers, this highlights the need to stratify outcomes not only by dose but also by starting weight, ensuring that comparisons across arms are meaningful

The starting dose is always 0.25 mg once weekly

Semaglutide is a medication that has gained attention for its effectiveness in managing type 2 diabetes and supporting medical weight loss
