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Some individuals notice appetite changes and early weight loss within the first few weeks, while more noticeable results may develop over several months

The glucagon receptor activation begins contributing noticeably to energy expenditure, creating a metabolic environment where the body burns more calories at rest than it did before treatment

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Effect of a new oral somatostatin analog (SDZ CO 611) on gastric emptying, mouth to cecum transit time, and pancreatic and gut hormone release in normal male subjects