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Zhong et al., 2021), the first oral GLP-1RA in the world, which provides effective glycemic control in type 2 diabetes when combined with diet and exercise intervention, bringing great convenience to patients (Davies et al., 2017

These medications help regulate appetite and reduce cravings, making it easier to follow a balanced, calorie-conscious approach without feeling deprived

Semaglutide's Mechanism and How Genetic Predispositions May Modulate Response Semaglutide acts as a GLP-1 receptor agonist, signaling satiety centers in the hypothalamus and modulating glucose homeostasis

This was accompanied by a reduction in glucose consumption and uptake in response to Exendin-4 (Fig

This may be attributed to differences in the type of GLP-1 agonist used, duration of use, the length of time the medication was held prior to the procedure, and fasting periods