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The NUD cohort included 21,160 cases and 21,160 controls (n=42,320)

[DOI] [PubMed] [Google Scholar] 64.Bradley M., Melchor J., Carr R., Karjoo S

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The impact on the nodular, fibrotic fat of the limbs remains variable

Before attributing symptoms to histamine intolerance, other conditions should be excluded according to UK guidelines, including: Food allergies (following BSACI guidance) Irritable bowel syndrome (NICE CG61) Coeliac disease (NICE NG20) Inflammatory bowel disease Red flags that warrant further investigation include unintentional weight loss, gastrointestinal bleeding, persistent vomiting, and iron-deficiency anaemia