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As we know, proteins involved in p-p38 and p-JNK are MAPKs pathways and p-AKT are all proteins belonging to PI3K/Akt pathway

A 2025 study published in the Journal of Periodontal Research found that GLP-1 receptor agonists may actually improve periodontal and peri-implant health in patients with type 2 diabetes

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Dehydration is a well-established cause of headache and may occur with GLP-1 medications due to reduced fluid intake (from appetite suppression) or increased fluid loss (from gastrointestinal side effects such as nausea, vomiting, or diarrhoea)

124 GLP-1, by activating its receptor, increases insulin secretion and reduces glucagon secretion, thereby lowering blood sugar levels

Tirzepatide (weekly) is a dual GIP/GLP-1 agonist with potentially greater results