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While these multi-agonist molecules demonstrate significant potential, their long-term cardiovascular outcome trials have not yet been completed, and long-term safety remains to be established [55]

[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Bremmer MP, Hendershot CS

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Those drugs mimic this hormone in a more sustained way than your body can on its own, since natural GLP-1 only sticks around in your bloodstream for a couple of minutes

It is not known if tirzepatide will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people