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Studies involving female cohorts were considered when relevant for mechanistic insights but were not used to extrapolate clinical conclusions regarding TRT

This makes it a promising future treatment for people who are living with obesity and/or type 2 diabetes

However, adequate adjustment of insulin doses and close monitoring after GLP-1RA initiation may decrease this risk

The more relevant concern is pharmacodynamic overlapmeaning both substances lower blood glucose and can theoretically amplify this effect together

Unfortunately, there have been no Phase III trials reported

It helps soften stool by drawing water into the small intestine, making it easier to go when you get up in the morning