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But, while these medications are powerful tools for health, theres a common problem that nobody told you to expect: constipation

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These results were observed in patients with T2DM who were inadequately controlled by diet and exercise alone and who had no prior experience with injectable diabetes therapy [70]

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In fact, nearly one third of all the NTS GLP-1-producing neurons send ascending fibers to the VTA and the NAc (core and shell regions) (Dossat et al., 2011