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Additionally, in high cardiovascular risk patients, the cardiac effects have been neutral, and other classes of antidiabetic medications (in particular SGLT-2 inhibitors or GLP-1 agonists) are preferred [63]

Recent headlines about Medicare GLP-1 price cuts for medications like Ozempic and Wegovy have generated significant patient interest and questions in weight loss practices across the country

doi: 10.1016/S2213-8587(18)30024-X [DOI] [PubMed] [Google Scholar] 31
Turek J et al

Drucker Peripherally administered GLP-1R agonists reduce food intake and body weight through signaling mechanisms requiring functional GLP-1Rs in the ARC of the hypothalamus
