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glp 1 agonist heart disease The cardiovascular effects of GLP-1 receptor agonists beyond obesity and type 2 diabetes: An anti-atherosclerotic action Effects of GLP-1 receptor agonists
Description
From this perspective, receptor-level signaling alone may be insufficient to ensure durable tissue-level outcomes

Its fermentable fibers produce beneficial short-chain fatty acids like butyrate, which help nourish the gut lining and support the natural activation of GLP-1 receptorsreinforcing the effects of your medication or healthy lifestyle, naturally.*

These are signs that the glucagon component is driving energy expenditure at a level that meaningfully contributes to the overall weight loss beyond what GLP-1 and GIP provide alone
A recent paper by Langer and colleagues is important because it tried to move beyond DXA-only thinking

More recently, due to the ongoing obesity epidemic and the better outcomes of the newer AOMs (i.e., GLP-1 medications), some plan sponsors are either choosing to add anti-obesity coverage in their pharmacy benefit or are at least considering doing so
Circulation 143 , e984e1010 (2021)
