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This delay can shift the timing of their peak concentration, potentially pushing their levels outside the safe and effective range

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Important Safety Information Who should not use tirzepatide: Type 1 diabetes patients (tirzepatide is not approved for type 1 diabetes) History of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

It plays a key role in glucose and appetite regulation by: Stimulating insulin release (glucose-dependent) Suppressing glucagon secretion Slowing gastric emptying Increasing satiety and reducing appetite In people with type 2 diabetes, this GLP-1 response is impaired leading to poor glycemic control

The 9mg dose beat that in 68 weeks