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The effect of GLP-1RA on the eGFR-related endpoint worsening kidney function was neutral in the main analysis (HR 0.86, 95% CI 0.721.02), while a statistically significant benefit was detected in the sensitivity analysis excluding ELIXA (HR 0.82, 95% CI 0.690.98) [11]

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One patient in the semaglutide group discontinued treatment due to severe nausea and vomiting, while the other patient in the metformin group discontinued treatment due to nausea and dyspepsia

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Nguyen AT, Mandard S, Dray C et al (2013) Lipopolysaccharides-Mediated increase in glucose-stimulated insulin secretion : involvement of the GLP-1 pathway

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GLP-1s are not yet available in all 50 states

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Exendin-4 was totally new to science and yet curiously familiar

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June 2024 Patent Highlights: GLP-1R Agonists, Pol Inhibitors, Non-Ab PD-L1 Inhibitors and More

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