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Aim for roughly 8 glasses (about 2 L) of water spread across the day

Journal of Young Pharmacists

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The joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society specifically flagged this concern

Rentzsch, P., Witten, D., Cooper, G

Both drugs prevented MPTP-induced motor impairment, protected dopaminergic neurons in the substantia nigra, reduced the expression of the proapoptotic signaling molecule Bax, and increased the levels of the antiapoptotic molecule Bcl-2 [87]