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These symptoms are usually temporary and tend to improve as the body gets used to the drug

But this relationship is not always linear, and individual variation plays a significant role

If these have not been investigated or are poorly controlled, discuss a targeted clinical review with your GP

Building a support system significantly improves outcomes

However, a dramatic shift occurred in late 2025

Considering the body weight reduction of more than 10% and the significant improvement in glycemic parameters without an increased risk of hypoglycemia, this trial establishes the efficacy and safety of the 7.2 mg dose of semaglutide compared with placebo in adults with obesity and type 2 diabetes, Lingvay and colleagues wrote.