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Options may include SGLT2 inhibitors, metformin, thiazolidinediones, or insulin for diabetes, noting that DPP-4 inhibitors also carry pancreatitis warnings

doi: 10.1093/jjco/hyy047 [DOI] [PubMed] [Google Scholar] 13

For the GCGR, however, cholesterol levels are negatively associated with receptor function as demonstrated by the fact that treatment with the cholesterol-lowering drug simvastatin increases ex vivo cAMP levels in response to GCG stimulation in murine hepatocytes (McGlone et al., 2022)

Nos, S
Significant effects of HM11260C (efpeglenatide) on body weight over 20 weeks in obese subjects without diabetes: a randomised, double-blind, placebo controlled study [abstract]