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Scale of projections: Estimates for Wegovy, Mounjaro, and Zepbound are based on Wall Street consensus projections, underscoring investor expectations for explosive growth and demand in the GLP-1 market

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Approvable documentation includes: "Patient has BMI 34.2 (measured 3/15/2026, height 5'6", weight 211 lbs) and hypertension (documented BP 148/94 on two visits)

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Antibodies targeting IL1- have also shown mixed, although more positive effects, particularly in reducing HbA1c with IL1- antagonism [206], with recent evidence suggesting that combined TNF-alpha and IL1- blockade may be most effective for glycemic control [207]

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J., D Seeger, J., Zhou, L., Ng, E., Ross, D., Major-Pedersen, A., Bosch-Traberg, H., Gydesen, H., & Dore, D

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