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however, close monitoring for gastrointestinal adverse events is warranted in cirrhotic patients, who may have reduced tolerance

Even the lowest tested dose of 1mg produced meaningful 8.7% average reduction
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Mol Cell (2001) 7(6):116576.10.1016/S1097-2765(01)00265-9 128 HuangCJHaatajaLGurloTButlerAEWuXSoellerWCet alInduction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

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NCT06857942), as well as investigations of semaglutide (NCT06475586), liraglutide, and exenatide (NCT01687582) in patients with T2DM