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Separately, the patent prosecution team manages continuation and continuation-in-part applications to ensure that the latest filings maintain live patent families connected to early priority dates, preserving the ability to capture broad coverage under older priority claims

Vomiting, diarrhea, constipation, and abdominal pain are also frequently experienced

Gastric motility also normalizes more gradually with a step-down, reducing the gastrointestinal discomfort some patients report when the drug's slowing effect disappears suddenly

The GLP-1 receptor agonist group was also less likely to have an adverse safety outcome than those receiving a DPP-IV inhibitor (HR = 0.9

resM, being a supplement with common botanical ingredients, is unlikely to cause significant side effects beyond mild digestive discomfort

A randomized clinical trial of the safety and efficacy of sitagliptin in patients with type 2 diabetes mellitus inadequately controlled by acarbose alone