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Mood changes, such as an increase in anxiety, are also common during perimenopause, but berberine may positively affect mental health by improving gut bacteria

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Yang X., Feng P., Zhang X., Li D., Wang R., Ji C., Li G., Hlscher C

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These changes may attenuate the inflammatory milieu that fuels AITD, in which adipose-derived cytokines such as TNF-, IL-6, and IL-17 are known to exacerbate the thyroidal immune attack [11,38]