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In the study which was not peer reviewed the researchers examined a cohort of 413,557 patients who had been prescribed tirzepatide, liraglutide (Saxenda, Novo Nordisk), dulaglutide (Trulicity, Eli Lilly), injectable semaglutide (Wegovy, Novo Nordisk) or oral semaglutide (Rybelsus, Novo Nordisk) for a minimum of 180 days

Clinical trials demonstrate significant weight loss with these medications when combined with lifestyle modifications

Key considerations include: Watching for signs of pancreatitis or gallbladder disease Looking at the patients overall health and medical history Changing the dosage or stopping treatment if side effects happen In patients with a history of gallbladder disease or cholecystectomy, the decision to start or keep using GLP-1 receptor agonist therapy should be made on a case-by-case basis

PlexusDx offers compounded tirzepatide injection starting at $249/month, as well as GLP-Squared Injectiona dual compound containing both semaglutide and tirzepatideto provide additional therapeutic options without switching providers

However, it is essential to note that this medication is unsuitable for individuals with type 1 diabetes or for managing diabetic ketoacidosis

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