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However, their use in T1D is not approved, even though they may have interesting effects

Exceptions are those with type 1 diabetes (who need insulin) or severe symptoms needing rapid glucose reduction

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How Tirzepatide and Semaglutide Work Differently in Your Body Semaglutide binds to GLP-1 receptors in your brain, pancreas, and digestive tract, slowing stomach emptying and increasing satiety signals

BMI measurements are counted at the start of GLP-1 therapy so even people who fall below the threshold now can qualify if they can show they had a high enough BMI when they began taking the drugs
