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Description
They talk about this a bit, but make the (odd, to me, at least) choice to compare the 104-week SELECT (cardiovascular) trial to the 68-week STEP 1 (weight loss) trial, rather than the 104-week STEP 5 (weight loss) Trial
Semaglutide is a glucagon-like peptide-1 receptor agonist that mimics your bodys GLP-1 hormone

This can make the switch financially viable even when brand coverage isnt available

However, it may also increase the risk of gastrointestinal side effects, so it's important to discuss this option and its side effect profile with your doctor

doi: 10.1016/S0140-6736(21)01443-4 73 Del PratoSKahnSEPavoIWeerakkodyGJYangZDoupisJet al

A summary of these findings is presented in Table 2
