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Tirzepatide, which is a dual GLP-1 and glucose-dependent insulinotropic peptide (GIP) receptor agonist, has shown even greater results in recent research

When food intake drops significantly, there is less material to stimulate those contractions

In the GLP-1 group, 76 of 145, 410 people developed thyroid cancer, and in the DPP4 group, 184 of 291, 667 developed the disease

Xu D, Nair A, Sigston C, et al

10.1016/S0140-6736(19)31271-1 Summary Keywords colorectal cancer, gastrointestinal cancer, GLP-1 receptor agonists, liver cancer, meta-analysis, obesity, oncological safety, pancreatic cancer Citation Wali AF, Rangraze I, Khan S, Mufti UB, El-Tanani M and Rizzo M (2026) Reassessing cancer risk with GLP-1 receptor agonists: a comprehensive meta-analysis of gastrointestinal malignancies

Graphs were prepared using GraphPad Prism (GraphPad Software, La Jolla, California, USA)