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Notably, the GLP-1R agonist liraglutide suppressed exogenous lactate-induced upregulation of the acetyltransferase p300, which has been identified as a writer of histone lactylation by transferring the lactyl group from lactyl-CoA to specific histone lysine residues [16]

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Elsharkawy: Formal analysis

2011;45(4):e22

33 The decrease in synovial DPP4 levels in RA may contribute to synovial inflammation through the SDF-1/CXCR4 axis, as the level of synovial SDF-1 was significantly correlated with inflammatory markers (serum C-reactive protein and IL-6) and disease activity score

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