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Eligibility criteria We included RCTs with a duration of intervention of at least 12 weeks that compared tirzepatide at a maintenance dose of 5, 10 or 15 mg once-weekly, administered subcutaneously, with placebo or any other glucose-lowering medication

Therefore, if you have a pre-existing liver disease, seek medical advice from your healthcare professional before starting tirzepatide

The prior 9-month / 10% guarantee required more extensive behavioral compliance and a longer timeline

Metabolism & Individual Differences Factors like age, genetics, hormones, and metabolic rate influence how quickly Tirzepatide facilitates weight loss

The reduction in the prevalence of patients meeting the criteria for metabolic syndrome observed with tirzepatide treatment in this SURPASS clinical trial program, and in particular in those with substantial weight loss, is within a similar range that has been previously reported with surgical intervention [46]

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