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First, inject the BAC water slowly into the vial at an angle so it runs down the glass wall rather than hitting the powder directly

Inject the air into the diluent vial, then draw the diluent into the syringe

And I think thats why, to a large extent, you see a really good response. Ozempic and Wegovy do the same thing as GLP-1 would normally do for you but to enable them to treat diabetes and obesity, not just the glucose impact of individual meals, theyve been designed, largely thanks to Knudsens work, with slight changes to allow them to hang out in the blood longer than GLP-1 normally does

Impact of Manufacturing Process and Compounding on Properties and Quality of Follow-On GLP-1 Polypeptide Drugs

Refrigeration acts as a powerful brake on this degradation process, dramatically slowing down the molecular motion and chemical reactions that lead to breakdown