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In the case of liraglutide, research demonstrated enhanced endothelial function via stimulation of the mammalian target of rapamycin complex 2/protein kinase B (mTORC2)/Akt pathway, resulting in increased NO production, elevated telomerase activity, and anti-apoptotic effects [115]

But systemic estrogen levels also matter, and adipose tissue is a significant source of estrogen production through peripheral aromatase conversion

We typically recommend stopping these medications at least 2 months before attempting conception

So, if someone gained weight and then started taking GLP-1 agonist medications, the end result result may not be exactly what that person looked like previously

Together, these components are presented not as a medical treatment, but as part of a broader discussion on how certain ingredients have been historically and contemporarily associated with energy, appetite, and balance in daily living

That is the metabolic hole many people fall into after stopping GLP-1 medication, and it helps explain why regain rates are so high