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Pre-treatment with propranolol protected against cerebral ischemia, edema and neuronal apoptosis
In medication-induced NAION cases, the small blood vessels supplying the optic nerve head become compromised

Nausea typically develops when doses increase too rapidly or when the medication first reaches its peak concentration in your bloodstream

175 Mitochondrial dysfunction is a defect in the early stage of PD and mainly includes impairment of the mitochondrial electron transport chain, alterations in mitochondrial morphology and dynamics, mutations in mitochondrial DNA, and anomalies in calcium homeostasis, 176 which are closely related to the PD phenotype

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