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Description
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The C20 fatty diacid moiety is attached to a lysine residue at position 20 via a gamma-glutamate and bis-aminodiethoxyacetyl linker, providing high affinity for albumin binding that prolongs circulating half-life

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Dosing follows a slow titration: 0.25 mg weekly for four weeks, then 0.5 mg, 1 mg, 1.7 mg, and finally 2.4 mg at week 17 if tolerated

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Semaglutide is given as a small weekly injection
