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In patients with FH, it is important to delineate between homozygous and heterozygous manifestations, as this can have extensive implications on treatment, management and the overall clinical prognosis and further disease sequelae that the patient may experience

doi: 10.2147/COPD.S393323

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Additionally, GCGR activation may indirectly influence fibrogenesis by modulating the hepatic metabolic milieu, reducing lipotoxicity and oxidative stress that serve as upstream triggers for fibrotic pathways (39, 47)
